Pharma

Stay updated with the latest happenings in the pharmaceutical industry. Get insights into drug development, innovations, regulatory updates, and emerging trends. Discover the advancements shaping the future of healthcare. Explore the world of pharma with our comprehensive coverage at Pharmtales.com.

2seventy bio, cell therapy, Cell & Gene Therapy, layoffs, sickle cell disease, beta-thalassemia, cell therapy setback, 2seventy bio layoffs

2seventy Bio slashes 176 jobs and looks for new CEO after cell therapy setback

Anika Sharma

2seventy bio, the spinoff from bluebird bio, is undergoing significant changes under the leadership of CEO Nick Leschly. The company ...

Septerna Therapeutics, Vertex Pharmaceuticals, Licensing deals, GPCR, GPCR-targeting drugs, Cystic fibrosis

Vertex partners with Septerna to develop GPCR-targeting drugs for rare diseases

Anika Sharma

Septerna, a biotech company, has secured an additional $47.5 million in funding through a licensing agreement with Vertex, a prominent ...

Arbutus Biopharma, COVID-19, hepatitis B, RNA degradation, preclinical data,

Arbutus scraps COVID-19 and RNA degradation programs after disappointing preclinical results

Anika Sharma

Arbutus Biopharma has made significant strategic shifts by discontinuing its involvement in COVID-19 research and RNA destabilizer programs, redirecting its ...

Acelyrin, clinical trial data, inflammatory diseases, failed trials, ulcerative colitis, phase 3 trial, IPO, stock price

Acelyrin’s lead drug flops in phase 3 trial, wiping out half of its market value

Anika Sharma

Acelyrin, a biotech company based in Los Angeles, has delivered a shocking blow to its investors. Despite successfully raising an ...

IASLC WCLC 2023 Conference - Tagrisso, a targeted therapy, combined with chemotherapy, extended the median progression-free survival by nearly 9 months in patients with EGFR-mutated advanced lung cancer, according to the FLAURA2 Phase III trial.

Tagrisso-chemo combo delays EGFR NSCLC progression by 9 months in first-line (IASLC WCLC 2023 Conference)

Anika Sharma

Against the formidable challenge of non-small cell lung cancer (NSCLC), AstraZeneca’s Tagrisso (osimertinib), when partnered with chemotherapy, has unveiled remarkable ...

IASLC WCLC 2023 Conference - Fasenra, a biologic medicine, met the primary endpoint of inducing remission in patients with eosinophilic granulomatosis with polyangiitis (EGPA), a rare and severe inflammatory disease.

Fasenra, a new treatment for EGPA, achieved remission in Phase III trial (IASLC WCLC 2023 Conference)

Anika Sharma

The MANDARA Phase III trial has shed new light on the effectiveness of AstraZeneca’s Fasenra (benralizumab). Unveiling favorable high-tier outcomes, ...

New drug Enhertu shows promise for HER2-mutant lung cancer patients (IASLC WCLC 2023 Conference)

New drug Enhertu shows promise for HER2-mutant lung cancer patients (IASLC WCLC 2023 Conference)

Anika Sharma

The International Association for the Study of Lung Cancer (IASLC) presented pivotal results from the DESTINY-Lung02 Phase II trial at ...

Aphexda, a novel drug from BioLineRx, helps more myeloma patients achieve stem cell collection goals for autologous transplantation, according to a Phase 3 trial.

FDA approves Aphexda for stem cell mobilization in multiple myeloma

Anika Sharma

After a decade of limited progress, the FDA has granted approval for the use of BioLineRx’s motixafortide, also known as ...

Alnylam, Onpattro, US FDA, FDA advisory committee, transthyretin amyloidosis, ATTR-cardiomyopathy

FDA doubts Onpattro’s benefit in heart disease, Alnylam faces Pfizer hurdle

Anika Sharma

The FDA has raised significant concerns about Alnylam’s attempt to expand the use of Onpattro for the treatment of transthyretin ...

Stelara, Sandoz, Samsung Bioepis, biosimilars, Tysabri, Eylea

Sandoz to market Samsung Bioepis’ biosimilar of Stelara in US and Canada

Anika Sharma

Sandoz is expanding its biosimilar portfolio by signing a commercialization agreement with Samsung Bioepis for a biosimilar version of Johnson ...

Theranos, Walgreens, blood test, fraud, settlement, lawsuit

Walgreens to pay $44 million to customers who bought faulty Theranos blood tests

Anika Sharma

Walgreens has reached a settlement in a long-running class-action case related to patients who underwent fraudulent blood tests provided by ...

Merck & Co., Acceleron, pulmonary arterial hypertension, clinical trial data, sotatercept, STELLAR, SOTERIA, ERS 2023, FDA

Merck showcases new data on sotatercept for PAH, awaits FDA decision

Anika Sharma

Merck & Co. has unveiled new clinical data on sotatercept, reinforcing the drug candidate’s safety and efficacy in the treatment ...

Bristol Myers Squibb, pulmonary fibrosis, idiopathic pulmonary fibrosis, BMS-986278, Phase 2 results

BMS scores another phase 2 win for its pulmonary fibrosis drug

Anika Sharma

Bristol Myers Squibb (BMS) is making significant strides in the field of pulmonary fibrosis treatment, particularly with its lysophosphatidic acid ...

Moderna has partnered with Immatics to develop mRNA-based cancer vaccines, bispecifics and cell therapies. The deal includes a $120 million upfront payment and up to $1.7 billion in milestones.

Moderna expands cancer vaccine portfolio with Immatics deal worth up to $1.7B

Anika Sharma

Moderna is intensifying its focus on cancer vaccines and cell therapies through a newly announced research partnership with Immatics, a ...

Novartis, Gyroscope Therapeutics, restructuring, eye disease, GT005, gene therapy, geographic atrophy, ophthalmology,

Novartis drops Gyroscope’s gene therapy for eye disease after disappointing trial results

Anika Sharma

Novartis is in the process of divesting its eye disease unit, a move that includes discontinuing a geographic atrophy (GA) ...

Novo Nordisk, J.P. Morgan, Eli Lilly, Wegovy, GLP-1, obesity, cardiovascular,

Novo Nordisk’s Wegovy boosts heart health, J.P. Morgan predicts $71B GLP-1 market by 2032

Anika Sharma

The demand for Novo Nordisk’s obesity medications is surging, with production capacity being the primary limiting factor in the short ...

Seagen, Nurix Therapeutics, Collaboration, ADC Technologies, antibody-drug conjugation, targeted protein degradation

Nurix and Seagen Join Forces to Pioneer Cancer Therapies by Combining Protein Degradation and ADC Technologies

Anika Sharma

Seagen has just sealed a strategic partnership with Nurix Therapeutics, headquartered in San Francisco. This collaboration is poised to unlock ...

World Conference on Lung Cancer, International Association for the Study of Lung Cancer IASLC 2023, Amgen, KRAS G12C NSCLC, Lumakras, Sotorasib, Chemotherapy

Amgen Unveils Exciting First-Line KRAS G12C NSCLC Data: Lumakras (Sotorasib) with Chemotherapy Shines at WCLC

Anika Sharma

Amgen has unveiled exciting findings from a segment of the CodeBreaK 101 clinical trial, a Phase 1b study investigating the ...

TROPION-Lung04, datopotamab deruxtecan, Dato-DXd, Imfinzi, NSCLC, International Association for the Study of Lung Cancer, IASLC 2023, Immunotherapy, antibody-drug conjugate

Datopotamab Deruxtecan + Imfinzi Transform First-Line NSCLC Treatment in TROPION-Lung04 Trial

Anika Sharma

The TROPION-Lung04 Phase Ib trial has unveiled highly promising results. The trial showcases the potential of datopotamab deruxtecan (Dato-DXd), in ...

Wilms Tumor, what causes this rare disease, how it is diagnosed and treated, and the chances of recovery. You may also want to know about the latest research and emerging therapies for this

Wilms Tumor: What You Need to Know

Anika Sharma

Let’s discuss about Wilms Tumor. You may wonder what causes this rare disease, how it is diagnosed and treated, and ...

National Health Service, Eli Lilly, Mounjaro, National Institute for Health and Care Excellence, NICE recommendation, Type 2 diabetes

Eli Lilly’s Mounjaro gets NICE approval for type 2 diabetes after cost-effectiveness review

Anika Sharma

Eli Lilly’s diabetes medication, Mounjaro (tirzepatide), has been on a winning streak since its US launch in May, and now ...

Bristol Myers Squibb, Celgene, Pomalyst, Patent fraud, reverse payments, lawsuit, Multiple myeloma

BMS faces lawsuit for allegedly extending Pomalyst monopoly with fraudulent patents and payoffs

Anika Sharma

Bristol Myers Squibb (BMS) and Celgene’s widely-used multiple myeloma treatment, Pomalyst, has found itself entangled in a legal battle after ...

Roche, Tecentriq, subcutaneous injection, subcutaneous Tecentriq, FDA setback, immunotherapy

Roche’s subcutaneous Tecentriq faces FDA setback due to manufacturing updates

Anika Sharma

Roche may experience a delay in the FDA decision for its subcutaneous version of the cancer immunotherapy Tecentriq, as it ...

Pfizer, Albert Bourla, migraine, awareness campaign, Nurtec ODT

Pfizer CEO supports migraine sufferers and urges employers to do the same

Anika Sharma

Pfizer’s CEO, Dr. Albert Bourla, is championing a disease awareness campaign by leveraging his social media platforms to underscore the ...

AstraZeneca and Verge partner to discover AI-driven drugs for rare neurodegenerative diseases

AstraZeneca and Verge partner to discover AI-driven drugs for rare neurodegenerative diseases

Anika Sharma

Verge Genomics is expanding its roster of Big Pharma partnerships by teaming up with AstraZeneca in a substantial $42 million ...

Asensus Surgical, Nvidia, Artificial intelligence, digital surgery, ISU, robotics, medtech

Asensus and Nvidia team up to boost AI-powered digital surgery solutions

Anika Sharma

Asensus Surgical, despite having secured approvals for its robotic and AI tools, is not resting on its laurels. The company ...

Ibex Medical Analytics, Artificial intelligence, Cancer diagnostics, funding, Breast cancer

Ibex raises $55M to expand its AI-powered cancer diagnostics in the US and beyond

Anika Sharma

Ibex Medical Analytics, an Israeli startup specializing in Artificial intelligence-powered cancer diagnostics, has secured an impressive $55 million in funding ...

ILIAD Biotechnologies, BPZE1, whooping cough, pertussis,nasal vaccine, Clinical trial results, CHAMPION-1 trial

ILiAD’s nasal vaccine prevents whooping cough infection in phase 2b trial

Anika Sharma

ILiAD Biotechnologies, a Florida-based biotech company, is celebrating a significant milestone in the development of its whooping cough vaccine. In ...

Otsuka Pharmaceutical, psychedelics, RNA technology, adeno-associated viruses, AAV vector, ocular diseases, Shape Therapeutics

Otsuka and Shape Therapeutics join forces to create gene therapies for eye diseases using AI-powered platform

Anika Sharma

Just a week after Otsuka Pharmaceutical ventured into the psychedelics sector, the Japanese pharmaceutical giant has struck a collaboration deal ...

Johnson & Johnson, Rybrevant, EGFR mutated NSCLC, Tagrisso, Osimirtinib, Clinical trial results, AstraZeneca

J&J’s Rybrevant Beats Chemo In Lung Cancer Patients Who Failed Tagrisso

Anika Sharma

The medical community buzzed with anticipation when Johnson & Johnson (J&J) released information about Rybrevant, their latest drug venture into ...