Roche and Ionis expand partnership with new RNA programs for Alzheimer’s and Huntington’s

Roche and Ionis expand partnership with new RNA programs for Alzheimer’s and Huntington’s

Roche, in its quest to find effective treatments for Alzheimer’s diseases after the setbacks of gantenerumab, has reaffirmed its commitment to seeking external partnerships. The pharmaceutical giant, in agreement with its long-term collaborator Ionis, is taking a new approach to tackle these challenging conditions. Roche is paying upfront payment of $60 million to secure exclusive … Read more

Ionis’ olezarsen slashes triglycerides and pancreatitis in rare disease patients

Ionis’ olezarsen slashes triglycerides and pancreatitis in rare disease patients

Ionis Pharmaceuticals has achieved a significant milestone in its phase 3 clinical trial for lipid-lowering therapy, bringing the company closer to seeking independent commercial approval. The trial focused on assessing the effects of Ionis’ ligand-conjugated antisense medicine, olezarsen, in patients with familial chylomicronemia syndrome (FCS), a rare condition. Notably, this marks Ionis’ first potential independent … Read more

Amylyx Pharmaceuticals Shines with ALS Drug’s Relyvrio’s Strong Performance and Promising Path Forward

Amylyx Pharmaceuticals Shines with ALS Drug's Relyvrio's Strong Performance and Promising Path Forward

Amylyx Pharmaceuticals continues to impress the financial world with its amyotrophic lateral sclerosis (ALS) drug, Relyvrio. The medication, known by a different name in Canada, generated an impressive $98.2 million in revenue during the second quarter, surpassing analysts’ estimates of around $92 million, according to Mizuho Securities. “Having annual revenue now tracking at $400 million … Read more

Novartis Invests $60 Million Upfront in Ionis’ Innovative Cardiovascular Medication

Novartis Teams Up with Ionis for New Lp(a) Drug

Source – Ionis Pharmaceuticals Novartis has enlisted Ionis to develop another drug for cardiovascular disease, investing $60 million in a “next-generation” drug aimed at targeting lipoprotein(a) (Lp(a)). This new drug builds upon the success of pelacarsen, an antisense-based Lp(a)-targeting drug that is currently in Phase III testing. The collaboration with Ionis is based on their … Read more

Alexion Acquires Voyager’s Preclinical Capsid for Rare Neurological Disease After $1B Pfizer Transfer

Alexion Gains Voyager's Preclinical Capsid in $1B Pfizer Handoff

Pfizer has transferred an AAV capsid designed for a rare neurological disease target to AstraZeneca’s rare disease subsidiary, Alexion, as part of a larger, previously announced bundled deal. This announcement, included in Voyager Therapeutics’ third-quarter earnings report, offers more details on a deal between Pfizer and Alexion that was initially disclosed in late July. At … Read more

Unlocking Hope: Curious Advances in Ewing Sarcoma Cancer Treatment, Paving the Way to Brighter Futures

Treatment of Ewing Sarcoma - Pharmtales

Ewing Sarcoma Cancer is a rare form of cancer that primarily affects the bones or the soft tissues surrounding them. Although it is most commonly diagnosed in children and young adults, it can occur at any age. Symptoms of Ewing sarcoma include pain, swelling, and occasionally fever or weight loss. The cancer has the potential … Read more