Clinical Trial Results
![BOTOX Cosmetic platysma prominence, OnabotulinumtoxinA Phase 3 study, Platysma muscle activity treatment, BOTOX Cosmetic M21-310 trial, Platysma prominence symptoms, BOTOX Cosmetic neck and jawline, OnabotulinumtoxinA FDA submission,](https://pharmtales.com/wp-content/uploads/2023/09/BOTOX®-Cosmetic-shows-promise-for-neck-and-lower-face-rejuvenation-in-phase-3-trial.jpg)
BOTOX Cosmetic shows promise for neck and lower face rejuvenation in phase 3 trial
Allergan Aesthetics, a subsidiary of AbbVie, has unveiled positive top-line findings from the second out of three Phase 3 clinical ...
![Anthos abelacimab trial, Blackstone ex-Novartis drug, Xarelto bleeding comparison, Anti-Factor XI/XIa antibody, Thrombosis without hemostasis, Novartis MAA868 history, Anthos phase 3 studies,](https://pharmtales.com/wp-content/uploads/2023/09/Anthos-ABP-959-outperforms-Xarelto-in-preventing-bleeding-events-in-phase-2-trial.jpg)
Anthos’ ABP-959 outperforms Xarelto in preventing bleeding events in phase 2 trial
Blackstone Life Sciences’ substantial $250 million investment in an ex-Novartis drug candidate has yielded yet another positive outcome in its ...
![ILIAD Biotechnologies, BPZE1, whooping cough, pertussis,nasal vaccine, Clinical trial results, CHAMPION-1 trial](https://pharmtales.com/wp-content/uploads/2023/09/ILiADs-nasal-vaccine-prevents-whooping-cough-infection-in-phase-2b-trial.jpg)
ILiAD’s nasal vaccine prevents whooping cough infection in phase 2b trial
ILiAD Biotechnologies, a Florida-based biotech company, is celebrating a significant milestone in the development of its whooping cough vaccine. In ...
![Johnson & Johnson, Rybrevant, EGFR mutated NSCLC, Tagrisso, Osimirtinib, Clinical trial results, AstraZeneca](https://pharmtales.com/wp-content/uploads/2023/09/JJs-Rybrevant-beats-chemo-in-lung-cancer-patients-who-failed-Tagrisso.jpg)
J&J’s Rybrevant Beats Chemo In Lung Cancer Patients Who Failed Tagrisso
The medical community buzzed with anticipation when Johnson & Johnson (J&J) released information about Rybrevant, their latest drug venture into ...
![Janssen, Johnson & Johnson, Cidara Therapeutics, Influenza, Clinical trial results](https://pharmtales.com/wp-content/uploads/2023/09/Janssen-Drops-Cidaras-Flu-Medicine-After-Disappointing-Phase-2-Results.jpg)
Janssen Drops Cidara’s Flu Medicine After Disappointing Phase 2 Results
Janssen is honoring its 2021 agreement with Cidara Therapeutics regarding the development of CD388, a flu prophylaxis treatment. However, Janssen ...
![Covid-19, Bavarian Nordic, COVID booster vaccine, Clinical trial results, Poor trial outcomes](https://pharmtales.com/wp-content/uploads/2023/09/Bavarian-Nordic-Abandons-COVID-Booster-After-Failing-to-Protect-Against-New-Variants.jpg)
Bavarian Nordic Abandons COVID Booster After Failing to Protect Against New Variants
Bavarian Nordic, a Danish biotech firm, has faced a crossroads that shines a light on the ever-evolving nature of the ...
![Tecentriq, Roche, Lung Cancer, NSCLC, Alecensa, Clinical trial results, ALK-positive NSCLC](https://pharmtales.com/wp-content/uploads/2023/09/Roches-Alecensa-beats-chemo-in-early-stage-lung-cancer-following-Tecentriqs-lead.jpg)
Roche’s Alecensa beats chemo in early-stage lung cancer, following Tecentriq’s lead
With Tecentriq approval, Roche is once again celebrating success, this time in a promising early-stage lung cancer trial starring Alecensa, ...
![Bristol Myers Squibb, Mezigdomide, Multiple Myeloma, Clinical trial results](https://pharmtales.com/wp-content/uploads/2023/08/Mezigdomide-a-new-oral-drug-for-multiple-myeloma-shows-‘modest-survival-benefit-in-phase-1-trial.jpg)
Mezigdomide, a new oral drug for multiple myeloma, shows ‘modest’ survival benefit in phase 1 trial
A new oral drug for multiple myeloma, mezigdomide, has shown a ‘modest’ survival benefit in a phase 1 trial involving ...
![Novocure, Electric fields, Ovarian cancer, Clinical trial results, Tumor Treating Fields technology, TTFields](https://pharmtales.com/wp-content/uploads/2023/08/Navigating-Peaks-and-Valleys_-Novocures-Tumor-Treating-Fields-Unveil-Divergent-Outcomes.jpg)
Navigating Peaks and Valleys: Novocure’s Tumor Treating Fields Unveil Divergent Outcomes
In the complex realm of medical breakthroughs, the journey from triumph to setback can be as unpredictable as it is ...
![BridgeBio Pharma, Amyloidosis, Clinical trial results, Acoramidis, European Society of Cardiology, Transthyretin amyloid cardiomyopathy](https://pharmtales.com/wp-content/uploads/2023/08/BridgeBio-Exposes-Phase-3-Acoramidis-Insights-Mortality-Figures.jpg)
BridgeBio Exposes Phase 3 Acoramidis Insights, Mortality Figures
In the intricate dance of scientific exploration, BridgeBio has taken a resolute plunge into the depths of phase 3 acoramidis ...
![Bayer, Cell Therapy, Parkinson’s Disease, Clinical trial results, Parkinson Cell Therapy,](https://pharmtales.com/wp-content/uploads/2023/08/Bayers-Parkinsons-Breakthrough_-Unveiling-Safety-Triumph-in-Cell-Therapy-Quest.jpg)
Bayer Advances Parkinson’s Cell Therapy to Phase 2 Trial
A new horizon gleams for Bayer’s quest to conquer Parkinson’s disease through advanced cell therapy. In a significant revelation, the ...
![Cabometyx, pancreatic cancer, Clinical trial results, Exelixis, Neuroendocrine Tumors](https://pharmtales.com/wp-content/uploads/2023/08/Exelixis-Celebrates-Early-End-to-Cabometyx-Trial-for-Neuroendocrine-Tumors-due-to-Remarkable-Efficacy.jpg)
Exelixis Celebrates Early End to Cabometyx Trial for Neuroendocrine Tumors due to Remarkable Efficacy
Exelixis, a drug developer, recently halted a cancer trial involving Cabometyx, their tyrosine kinase inhibitor, due to an overwhelming display ...
![Roche, Lung Cancer, TIGIT, Tecentriq, tiragolumab, Clinical trial results, NSCLC](https://pharmtales.com/wp-content/uploads/2023/08/Roche-Unveils-Interim-TIGIT-Overall-Survival-Data-Following-Unintended-Release-Triggering-Surge-in-Stocks.jpg)
Roche Unveils Interim TIGIT Overall Survival Data Following Unintended Release, Triggering Surge in Stocks
An unexpected revelation has provided the world with a sneak peek into Roche’s highly anticipated TIGIT data. Roche, which had ...
![Novartis Drug Remibrutinib Cures Hives in Weeks](https://pharmtales.com/wp-content/uploads/2023/08/How-Remibrutinib-a-Novartis-Drug-Can-Heal-Your-Hives.png)
How Remibrutinib, a Novartis Drug, Can Heal Your Hives
Source – Novartis Novartis has unveiled promising initial outcomes from the Phase III REMIX-1 and REMIX-2 trials assessing the effectiveness ...
![Apogee Doses First Patients in Phase I Trial of APG777](https://pharmtales.com/wp-content/uploads/2023/08/Phase-I-Trial-of-APG777-a-New-Antibody-for-Inflammation-Begins.jpg)
Apogee Doses First Patients in Phase I Trial of APG777
Source – Apogee Therapeutics Apogee Therapeutics has embarked on a significant milestone by commencing the dosing of healthy volunteers in ...
![Batiraxcept Does Not Improve Survival in Ovarian Cancer Patients](https://pharmtales.com/wp-content/uploads/2023/08/PFS-in-Patients-with-Platinum-Resistant-Ovarian-Cancer-Is-Not-Improved-by-Batiraxcept.jpg)
PFS in Patients with Platinum-Resistant Ovarian Cancer Is Not Improved by Batiraxcept
Source – Aravive The Phase III AXLerate-OC trial (NCT04300140) assessing the combination of batiraxcept with paclitaxel has not met its ...
![Bavarian Nordic Beats Valneva in Chikungunya Vaccine Race](https://pharmtales.com/wp-content/uploads/2023/08/Bavarian-Nordics-Chikungunya-Vaccine-Shines-in-Phase-III-Trials-Poses-Strong-Challenge-to-Valnevas-Dominance.jpg)
Bavarian Nordic’s Chikungunya Vaccine Shines in Phase III Trials, Poses Strong Challenge to Valneva’s Dominance
Source – Bavarian Nordic Bavarian Nordic has achieved a significant milestone with its chikungunya virus vaccine candidate, marking its second ...
![Tirzepatide: Eli Lilly’s Breakthrough Drug for Obesity](https://pharmtales.com/wp-content/uploads/2023/07/Eli-Lillys-Tirzepatide-Succeeds-in-2-More-Late-Stage-Obesity-Trials-Ahead-of-FDA-Decision.jpg)
Eli Lilly’s Tirzepatide Succeeds in 2 More Late-Stage Obesity Trials Ahead of FDA Decision
Source – Eli Lilly Eli Lilly continues to gather strong evidence supporting the effectiveness of tirzepatide, its dual GIP/GLP-1 agonist, ...
![Merck’s V116 Vaccine Proves Effective in Phase III Trials](https://pharmtales.com/wp-content/uploads/2023/07/Mercks-V116-Vaccine-Shows-Positive-Results-in-Phase-III-Trials.jpg)
Merck’s V116 Vaccine Shows Positive Results in Phase III Trials
Source – Merck Merck, known as MSD outside of the United States and Canada, has announced highly encouraging initial results ...
![New Vaccine Combo May Cure Deadly Melanoma](https://pharmtales.com/wp-content/uploads/2023/07/Merck-and-Moderna-Commence-Phase-III-Study-of-V940-with-KEYTRUDA-for-High-Risk-Melanoma.jpg)
Merck and Moderna Commence Phase III Study of V940 with KEYTRUDA for High-Risk Melanoma
Source – Merck Moderna and Merck announced the commencement of the pivotal Phase III randomized V940-001 clinical trial. This trial ...
![PANOVA-3 Trial Tests TTFields for Pancreatic Cancer Survival](https://pharmtales.com/wp-content/uploads/2023/07/Continue-to-Evaluate-TTFields-in-Pancreatic-Cancer-in-the-PANOVA-3-Trial.jpg)
Continue to Evaluate TTFields in Pancreatic Cancer in the PANOVA-3 Trial
Source – Novocure The Phase III PANOVA-3 trial, which is assessing Tumor Treating Fields (TTFields) therapy in combination with nab-paclitaxel ...
![ADC Therapeutics Halts LOTIS-9 Trial of Zynlonta for DLBCL Patients](https://pharmtales.com/wp-content/uploads/2023/07/Discontinuation-of-LOTIS-9-Trial_-Zynlonta-in-Unfit-DLBCL-Patients.jpg)
Discontinuation of LOTIS-9 Trial: Zynlonta in Unfit DLBCL Patients
Source – ADC Therapeutics On July 20, 2023, ADC Therapeutics announced its decision to discontinue the Phase II LOTIS-9 clinical ...
![Merck’s KEYNOTE-A18 Trial Shows Breakthrough in Cervical Cancer Treatment](https://pharmtales.com/wp-content/uploads/2023/07/KEYNOTE-A18-Trial_-Primary-Endpoint-Progression-Free-Survival-in-High-Risk-Cervical-Cancer.jpg)
KEYNOTE-A18 Trial: Primary Endpoint – Progression-Free Survival in High-Risk Cervical Cancer
Source – Merck Merck has announced a groundbreaking development in its Phase III KEYNOTE-A18 trial, also referred to as ENGOT-cx11/GOG-3047. ...
![How Hearing Aids Can Help Prevent Cognitive Decline in Some People](https://pharmtales.com/wp-content/uploads/2023/07/Some-individuals-cognitive-deterioration-may-be-slowed-by-hearing-aids.jpg)
Some individuals’ cognitive deterioration may be slowed by hearing aids
Amid the focus on expensive therapies targeting amyloid for Alzheimer’s disease, a new clinical study highlights an alternative approach to ...
![Lazertinib Beats Gefitinib in Treating EGFR-Mutated NSCLC](https://pharmtales.com/wp-content/uploads/2023/07/Lazertinib-Beats-Gefitinib-in-Treating-EGFR-Mutated-NSCLC.jpg)
Lazertinib Beats Gefitinib in Treating EGFR-Mutated NSCLC
In a Phase III study known as LASER301 (NCT04248829) and published in the Journal of Clinical Oncology, lazertinib (formerly YH25448), ...
![BridgeBio Reports Improved Data for ATTR Cardiomyopathy Drug](https://pharmtales.com/wp-content/uploads/2023/07/BridgeBio-improves-on-data-for-ATTR-cardiomyopathy.jpg)
BridgeBio Reports Improved Data for ATTR Cardiomyopathy Drug
Source – BridgeBio BridgeBio is preparing to seek FDA approval for its acoramidis drug to treat transthyretin amyloidosis (ATTR) cardiomyopathy, ...
![Treatment for Advanced HNSCC With ASP-1929 and Anti-EGFR Therapy Is Effective](https://pharmtales.com/wp-content/uploads/2023/07/Treatment-for-Advanced-HNSCC-With-ASP-1929-and-Anti-EGFR-Therapy-Is-Effective.jpg)
Treatment for Advanced HNSCC With ASP-1929 and Anti-EGFR Therapy Is Effective
Source – Rakuten Medical Promising early results have been observed with ASP-1929, in combination with anti-PD-1 therapy, for patients with ...
![latest News In Pharma](https://pharmtales.com/wp-content/uploads/2023/07/First-Wave-BioPharmas-Pancreatic-Enzyme-Replacement-Therapy-Faces-Hurdles-Stock-Plummets.jpg)
First Wave BioPharma’s Pancreatic Enzyme Replacement Therapy Faces Hurdles, Stock Plummets
Source – First Wave BioPharma First Wave BioPharma, formerly known as AzurRx BioPharma, has faced ongoing challenges in bringing a ...
![Promising Phase III Results: OCREVUS (Ocrelizumab) Subcutaneous Injection Offers Convenient and Efficient Treatment for Multiple Sclerosis](https://pharmtales.com/wp-content/uploads/2023/07/Promising-Phase-III-Results_-OCREVUS-Ocrelizumab-Subcutaneous-Injection-Offers-Convenient-and-Efficient-Treatment-for-Multiple-Sclerosis.jpg)
Promising Phase III Results: OCREVUS (Ocrelizumab) Subcutaneous Injection Offers Convenient and Efficient Treatment for Multiple Sclerosis
Source – Roche On 13 July Roche announced positive results from the Phase III OCARINA II trial, which investigated the ...